구강세균이 뇌졸중의 위험 을 증가시킨다.

? Michael Jurgelewicz, DC, DACBN, DCBCN

?최근에 구강에 대한 ?????

In a recent study published this month in?Scientific Reports, researchers at the University of Louisville School of Medicine have gained new insight into the association between different types of stroke and the presence of the oral bacteria,?Streptococcus mutans.?S. mutans?is a major pathogen of dental caries (also known as tooth decay,?cavities)?and causes bacteremia by dental procedures.

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In this new study, researchers observed 100 acute stroke patients to better understand the relationship between hemorrhagic stroke and oral bacteria. In the patients who experienced intracerebral hemorrhage (ICH), 26% were found to have?cnm-positive?S. mutans?in the saliva. Among patients with other types of stroke, only 6% tested positive. Researchers found that the?cnm-positive?S. mutans?contributes to the development of ICH by expressing a collagen-binding protein that the?cnm?gene encodes on the bacterial surface, which disrupts the blood-brain barrier.?

The researchers also evaluated MRIs of the participants for the presence of cerebral microbleeds (CMB), which are small brain hemorrhages that may cause dementia and also often underlie ICH. They found that the number of CMBs were significantly higher in subjects with?cnm-positive?S. mutans?than in those without.

The dental caries-causing?cnm-negative?S. mutans?bacteria is found in approximately 10% of the population. Various research studies have shown a close association between gum disease and both heart disease and rheumatoid arthritis. Researchers are exploring the role of oral bacteria in other neurodegenerative disorders such as Alzheimer's and Parkinson's disease. With all of this information, we see that it is essential to have good oral hygiene because it impacts the rest of the body.

Two therapies to consider for overall oral health are?silver?and Dental-Lac. Silver is a highly effective broad-spectrum antimicrobial that can be used before, during, and after dental procedures. It supports the immune system, has no side effects, and does not interfere with antibiotics. Dental-Lac is a patent pending and clinically tested specific?Lactobacillus paracasei?strain that has been show to kill off harmful strains of harmful bacteria, including?S. mutans.